Best of San Luis, AZ
The best restaurants, cafés, bars, shops and things to do in San Luis, AZ — mapped and organized by category.
About San Luis
San Luis is a city in Yuma County, Arizona, situated in the southwest corner of the state directly adjacent to Mexico's Federal Highway 2 at San Luis Río Colorado, Sonora. It was the second fastest-growing city or town in Arizona from 1990 to 2000 and remains part of the Yuma County Metropolitan Statistical Area. According to 2025 Census Bureau estimates, the population of the city is 42,030.
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653 Hotel
The 653 Hotel is a lodging option located in the Los Alamos neighborhood.
View details →Best Hotels in San Luis
10 places · Where to stay, from budget-friendly to boutique.
Nearby cities to explore
More guides within driving distance of San Luis.
- San Luis Río Colorado, SON 72 places
- Ejido Hermosillo, BCN 2 places
- Somerton, AZ 9 places
- Tecolotes, BCN 8 places
- Fortuna Foothills, AZ 13 places
- Mexicali, BCN 252 places
- Santa Isabel, BCN 55 places
- San Felipe, BCN 22 places